6803-19-6
6803-19-6
Chemical Structure
S-(p-Nitrobenzyl)glutathione
- CAS No.: 6803-19-6
- Formula:C17H22N4O8S
- Molecular Weight:442.44
IUPAC Name: N5-((R)-1-((carboxymethyl)amino)-3-((4-nitrobenzyl)thio)-1-oxopropan-2-yl)-L-glutamine
InChIKey: OAWORKDPTSAMBZ-STQMWFEESA-N
SMILES: OC([C@@H](N)CCC(N[C@H](C(NCC(O)=O)=O)CSCC1=CC=C(C=C1)[N+]([O-])=O)=O)=O
Biological Activity: S-(p-Nitrobenzyl)glutathione is a competitive glutathionase inhibitor. S-(p-Nitrobenzyl)glutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-(p-Nitrobenzyl)glutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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S-(p-Nitrobenzyl)glutathione | 98.99% | S-(p-Nitrobenzyl)glutathione is a competitive glutathionase inhibitor. S-(p-Nitrobenzyl)glutathione is converted to the corresponding cysteine derivatives by rat kidney microsomes. S-(p-Nitrobenzyl)glutathione can be used for the research of metabolic breakdown of glutathione by the glutathionase system. | ||||||||||||||||||||
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References
- [1]. I García-Sáez, et al. Molecular structure at 1.8 A of mouse liver class pi glutathione S-transferase complexed with S-(p-nitrobenzyl)glutathione and other inhibitors. J Mol Biol. 1994 Apr 1;237(3):298-314. [Content Brief]
- [2]. T Suga, et al. Studies on mercapturic acids. Participation of glutathionase in the conversion of glutathione derivatives to cysteine derivatives. J Biochem. 1966 Aug;60(2):133-9. [Content Brief]
