1 Result for "

H052

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "H052" in MCE Product Catalog:

Cat. No.: HY-173526
CAS No.: 2886748-00-9
Research Areas:  

Infection

H052 is a selective Staphylococcus aureus α-hemolysin (Hla) inhibitor. H052 binds to Hla monomers, disrupts the interaction with host cell membranes to block pore formation, inhibiting calcium ion influx, cytotoxicity, and inflammatory responses. H052 exhibits potency (EC50=30 nM in U937 cells) against Hla-induced calcium influx. H052 is promising for research of lung infections caused by S. aureus .
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