1 Result for "

H2170

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "H2170" in MCE Product Catalog:

製品番号: HY-150023
CAS 番号: 2681392-19-6
純度:  98.97%
Target:  

EGFR Itk PI4K Btk CDK Raf JAK

研究分野:  

Cancer

BI-1622 is an orally active, potent and highly selective HER2 (ERBB2) inhibitor, with an IC50 of 7 nM. BI-1622 shows greater than 25-fold selectivity over EGFR. BI-1622 shows high antitumor efficacy in vivo in xenograft mouse tumor models with engineered H2170 and PC9 cells and had a favorable agent metabolism and pharmacokinetics profile .
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