1 Result for "

HGS101

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HGS101" in MCE Product Catalog:

Cat. No.: HY-P991541

Target:  

CCR HIV

Research Areas:  

Infection

HGS101 is a fully human CCR5 monoclonal antibody with high affinity to CCR5. HGS101 binds to the 2nd extracellular loop (ECL-2) and acts as a signal antagonist. HGS101 restores Maraviroc (HY-13004) inhibition of Maraviroc-resistant HIV-1 infection of PBMCs. HGS101 shows anti-HIV activity by inhibiting CCR5 signaling in simian immunodeficiency virus-uninfected RMs models .
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