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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
HIF-IN-3
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "HIF-IN-3" in MCE Product Catalog:
Cat. No.: HY-189519
CAS No.: 1783134-96-2
Target:
Research Areas:
HIF-IN-3 is a HIF inhibitor. HIF-IN-3 blocks the dimerization of HIF-α with HIF-1β by binding to the PAS domain of HIF-α, and induces the degradation of HIF-1α and HIF-2α via the ubiquitin-proteasome pathway. HIF-IN-3 inhibits the expression of the endogenous HIF-1 target gene CA9 and the HIF-2 target gene EPO in cancer cells. HIF-IN-3 inhibits tumor growth in the BT-474 breast cancer model. HIF-IN-3 can be used for research on HIF-related tumors such as breast cancer, colorectal cancer, and head and neck squamous cell carcinoma .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
