2 Results for "

HIV-infected primary cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "HIV-infected primary cells" in MCE Product Catalog:

Cat. No.: HY-P991479
CAS No.: 2839531-84-7
Synonyms: GS-8588

Target:  

HIV CD3

Research Areas:  

Infection

Amtabafusp alfa (GS-8588) is an envelope-targeting bispecific T-cell engager for HIV treatment. Amtabafusp alfa redirects effector T cells by binding to CD3 via a humanized anti-CD3 Fab domain and to HIV envelope proteins via an engineered CD4 domain 1 variant. Amtabafusp alfa exhibits potent, broad-spectrum activity against a variety of HIV isolates and specifically kills HIV-infected cells. Amtabafusp alfa can be used for research on HIV infection .
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Cat. No.: HY-184379
CAS No.: 2358714-71-1
Target:  

HIV

Research Areas:  

Infection

SRI-37264 is a HIV-1 Nef inhibitor with a Kd value of 162 nM. SRI-37264 binds directly to HIV-1 Nef, disrupts the Nef·MHC-I·AP-1 μ1 complex, and inhibits the Nef-dependent enhancement of HIV-1 infectivity. SRI-37264 restores MHC-I expression on the surface of HIV-infected primary cells. SRI-37264 inhibits HIV-1 replication in primary macrophages. SRI-37264 is applicable to research related to HIV-1 infection .
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