3 Results for "

HMBPP

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "HMBPP" in MCE Product Catalog:

Art. -Nr.: HY-134891
CAS. Nr.: 396726-03-7
Reinheit:  ≥95.0%
Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium
HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos .
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Art. -Nr.: HY-163836
Target:  

Drug Derivative

Forschungsgebiete:  

Others

HMBPP analog 1 (6e), a Trifluoromethyl analog, is the weakest agonist but the strongest inhibitor HMBPP ELISA response .
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Art. -Nr.: HY-186052
4-M-HMBPP is a weak agonist for Vγ9Vδ2 T cell activation and a potent competitive inhibitor of HMBPP. 4-M-HMBPP binds to BTN3A1 with high affinity (KD: 26.2 μM), but fails to induce its complex formation with BTN2A1. 4-M-HMBPP can be used in studies on γδ T cell activation .
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