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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
12 Results for "
HMGB1-IN-1
" in MedChemExpress (MCE) Product Catalog:
Products (12)
12 Results for "HMGB1-IN-1" in MCE Product Catalog:
Cat. No.: HY-155751
Purity: 99.37%
Research Areas:
HMGB1-IN-1 (compound 6) displays strong NO inhibitory effect in RAW264.7 cells with IC50 value of 15.9 ± 0.6 μM. HMGB1-IN-1 inhibit the HMGB1/NF-κB/NLRP3 pathway. HMGB1-IN-1 shows good anti-inflammatory activity and good anti-sepsis effects in kidney injury .
2
2 Cited Publications
Synonyms: MagnoflorINe chloride; α-MagnoflorINe chloride; ThalictrINe chloride
2
2 Cited Publications
Synonyms: MagnoflorINe iodide; α-MagnoflorINe iodide; ThalictrINe iodide
1
Research Areas:
1
1 Cited Publications
Cat. No.: HY-162065
CAS No.: 851398-76-0
Target:
Research Areas:
N6F11 is a selective ferroptosis inducer, and can selectively induce ferroptosis by targeting TRIM25-mediated GPX4 degradation in cancer cells while sparing immune cells. N6F11 initiates HMGB1-dependent antitumor immunity mediated by CD8 + T cells .
1
1 Cited Publications
Target:
Free Radical Scavengers TNF Receptor Interleukin Related Toll-like Receptor (TLR) Reactive Oxygen Species (ROS)
Research Areas:
NecroX-7 is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor. NecroX-7 can be used as an antidote to acetaminophen toxicity. NecroX-7 exerts a protective effect by preventing the release of HMGB1 in ischemia/reperfusion injury. NecroX-7 inhibits the HMGB1-induced release of TNF and IL-6, as well as the expression of TLR-4 and receptor for advanced glycation end products. NecroX-7 can be used graft-versus-host disease (GVHD) research .
1
1 Cited Publications
Cat. No.: HY-P9928A
CAS No.: 1245916-14-6
Synonyms: REGN 727(anti-PCSK9); SAR 236553(anti-PCSK9)
Research Areas:
Cat. No.: HY-N0442
CAS No.: 84272-85-5
Synonyms: 4'-O-β-D-Glucosyl-5-O-methylvisammINol
Cat. No.: HY-143456
CAS No.: 2873386-66-2
Target:
Research Areas:
Anti-inflammatory agent 18 (compound 3b) shows NO inhibitory activity, with an IC50 of 15.94 μM. Anti-inflammatory agent 18 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 18 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
Cat. No.: HY-143457
CAS No.: 2873386-63-9
Target:
Research Areas:
Anti-inflammatory agent 19 (compound 2b) shows NO inhibitory activity, with an IC50 of 36.00 μM. Anti-inflammatory agent 19 inhibits HMGB1-induced later inflammation. Anti-inflammatory agent 19 can be used for the research of later inflammation diseases such as coronavirus diseases (COVID-19) and sepsis, etc .
Cat. No.: HY-N0442R
CAS No.: 84272-85-5
Synonyms: 4'-O-β-D-Glucosyl-5-O-methylvisammINol (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
