1 Result for "

HuZAF

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HuZAF" in MCE Product Catalog:

Cat. No.: HY-P99292
CAS No.: 326859-36-3
Synonyms: HuZAF; Anti-Human IFNG Recombinant Antibody

Target:  

IFNAR

Research Areas:  

Inflammation/Immunology

Fontolizumab (HuZAF) is a human monoclonal antibody targeting interferon γ (IFN-γ). Fontolizumab binds specifically and with high affinity to secreted IFN-γ, neutralizes its activity, blocks receptor binding, and inhibits downstream signal transduction and the expression of IFNγ-responsive genes. Fontolizumab reduces serum C-reactive protein levels, inhibits the expression of IL-1α, IL-1β and IL-12Rβ2, and decreases the number of IFNγ-producing T cells in activated peripheral blood mononuclear cells. Fontolizumab can be used in research related to Crohn's disease .
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