2 Results for "

IFNB1 mRNA

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IFNB1 mRNA" in MCE Product Catalog:

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Cat. No.: HY-174664
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IFNB1 mRNA encodes the human interferon beta 1 (IFNB1) protein, a cytokine that belongs to the interferon family. IFNB1 belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses.
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Cat. No.: HY-178951
CAS No.: 3069635-58-8
STING-IN-17 (compound 10a) is an orally active STING (human STING IC50 = 29 nM, mouse STING IC50 = 15 nM) inhibitor. STING-IN-17 can inhibit the phosphorylation of STING, TBK1 and IRF3. STING-IN-17 dose dependently inhibits the mRNA expression of IP10, IFNB1 and ISG56. STING-IN-17 can reduce ROS and inhibit the expression of cleaved-PARP/caspase-3. STING-IN-17 can improve kidney function. STING-IN-17 can be used for research on inflammatory conditions such as acute kidney injury .
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