27 Results for "

IL-23 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (27)

27 Results for "IL-23 receptor" in MCE Product Catalog:

Cat. No.: HY-P10587
CAS No.: 2763602-16-8
Synonyms: JNJ-77242113; JNJ-2113; PN-235
Research Areas:  

Inflammation/Immunology

Icotrokinra (JNJ-77242113) is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-γ production in NK cells with an IC50 of 18.4 pM. Icotrokinra exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra can be used in the study of psoriasis, psoriatic arthritis, and inflammatory bowel disease .
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Cat. No.: HY-P10723
CAS No.: 2894052-23-2
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

IL-23R inhibitor peptide-1 (comp 475) is an interleukin-23 receptor inhibitor, with an IC50 of 0.0069 μM .
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Cat. No.: HY-P10587A
Synonyms: JNJ-77242113 acetate; JNJ-2113 acetate; PN-235 acetate
Research Areas:  

Inflammation/Immunology

Icotrokinra (JNJ-77242113) acetate is an orally available, selective antagonist of the IL-23 receptor. Icotrokinra acetate inhibits IL-23-induced STAT3 phosphorylation in peripheral blood mononuclear cells (IC50=5.6 pM) and inhibits IL-23-induced interferon IFN-γ production in NK cells with an IC50 of 18.4 pM. Icotrokinra acetate exhibits anti-inflammatory activity in a rat TNBS-induced colitis model. Icotrokinra acetate can be used in the study of psoriasis, psoriatic arthritis, and inflammatory bowel disease .
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Cat. No.: HY-150733
CAS No.: 3032075-32-1
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

IRAK4-IN-19 is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 value of 4.3 nM. IRAK4-IN-19 can inhibit LPS-induced IL23 production in THP and DC cells, and stop arthritis development in arthritis rats. IRAK4-IN-19 can be used for researching arthritis disease .
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Cat. No.: HY-168971
CAS No.: 1390658-79-3
Synonyms: CP-25
Paeoniflorin-6′-O-benzene sulfonate (CP-25) is the inhibitor for G protein-coupled receptor kinase 2 (GRK2) that inhibits the translocation of GRK2 to the cell membrane, inhibits JAK1/STAT3 signaling pathway. Paeoniflorin-6′-O-benzene sulfonate inhibits IL-17A/CXCL2-induced proliferation of HaCaT. Paeoniflorin-6′-O-benzene sulfonate reduces the levels of inflammatory factors and chemokines such as IL-17A, IL-17F, IFN-γ, TNF-α, IL-22, IL-23, CXCL2, CXCL3 and CXCL9, alleviates Imiquimod (HY-B0180)-induced psoriasis in mouse model .
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Cat. No.: HY-174616
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL23R mRNA encodes the human interleukin 23 receptor (IL23R) protein, a subunit of the receptor for IL23A/IL23. IL23R pairs with the receptor molecule IL12RB1/IL12R beta1, and both are required for IL23A signaling.
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Cat. No.: HY-P83656
Synonyms: Interleukin-23 receptor; IL23 receptor; IL23R; IL 23R; interleukin 23 receptor; IL-23 receptor; IL23R_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human

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Cat. No.: HY-P73197
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P73885
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P73886
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75857
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P73196
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-150732
CAS No.: 3032075-26-3
Target:  

IRAK

Research Areas:  

Inflammation/Immunology

IRAK4-IN-18 is a potent interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with an IC50 value of 15 nM. IRAK4-IN-18 can inhibit LPS-induced IL23 production in THP and DC cells, and stop arthritis development in arthritis rats. IRAK4-IN-18 can be used for researching arthritis disease .
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Cat. No.: HY-P78470
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P701011
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Canine
Source:  
HEK293
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Cat. No.: HY-P704701
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P700889
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P703678
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Rat
Source:  
HEK293
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Cat. No.: HY-P78856
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P700746
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL23R; IL-23 receptor; Interleukin 23 receptor; IL23RL1-THE1A; Interleukin-23 receptor; PSORS7; IL-23R
Species:  
Mouse
Source:  
HEK293
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