23 Results for "

IL-7 receptor

" in MedChemExpress (MCE) Product Catalog:
Products (23)

23 Results for "IL-7 receptor" in MCE Product Catalog:

Referencia número: HY-P990774
No. CAS: 2768386-15-6
Synonyms: ASP-7266; TRAB-1; UPB-101

Target:  

Interleukin Related

Áreas de investigación:  

Inflammation/Immunology

Verekitug (ASP-7266; TRAB-1; UPB-101) is a human monoclonal antibody targeting the thymic stromal lymphopoietin receptor (TSLPR), with a mean half-life of approximately 20 days. At doses of Verekitug ≥100 mg, complete and sustained TSLPR-specific occupancy is achieved, and the antibody does not bind to IL-7Rα. By inhibiting TSLP-driven inflammatory responses, Verekitug blocks TSLP-induced cell proliferation and TARC expression, while reducing fractional exhaled NO levels, blood eosinophil counts, and levels of IL-5 and IgE. Verekitug significantly improves scores for nasal polyps, nasal congestion and olfactory dysfunction, with favorable safety and good tolerability; potential adverse reactions include headache, upper respiratory tract infection, sinusitis and nasopharyngitis. Verekitug is used in relevant studies on asthma, chronic rhinosinusitis with nasal polyps and chronic obstructive pulmonary disease .
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Referencia número: HY-P991424

Áreas de investigación:  

Inflammation/Immunology

GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used for the research of autoimmune and allergic inflammatory diseases. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Referencia número: HY-P991720
No. CAS: 2985643-31-8

Target:  

Interleukin Related

Áreas de investigación:  

Inflammation/Immunology

Tepilukimig is a bivalent humanized IgG1κ monoclonal antibody inhibitor targeting TSLP-IL7 and TSLP-CRLF2. Tepilukimig inhibits the binding of TSLP to its receptors (IL7Rα and CRLF2) on the cell surface, thereby completely interrupting the inflammatory signaling pathway driven by TSLP. Tepilukimig can be used for allergic and inflammatory diseases like atopic dermatitis and asthma research .
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Referencia número: HY-174597
Target:  

mRNA

Áreas de investigación:  

Inflammation/Immunology

Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
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Referencia número: HY-P80593
Synonyms: IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Referencia número: HY-P80593A
Synonyms: IL7R; Interleukin-7 receptor subunit alpha; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; CDw127; CD antigen CD127

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Referencia número: HY-P72537
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P76436
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Mouse
Source:  
HEK293
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Referencia número: HY-P77011
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Rat
Source:  
HEK293
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Referencia número: HY-P77425
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Cynomolgus
Source:  
HEK293
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Referencia número: HY-P703696
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P72536
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Mouse
Source:  
HEK293
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Referencia número: HY-P77012
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Rat
Source:  
HEK293
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Referencia número: HY-P704720
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P704721
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P704722
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P7785
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P705229
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P76433
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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Referencia número: HY-P704719
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL7R; Soluble Interleukin-7 receptor; Interleukin 7 receptor; IL-7 receptor Subunit Alpha; CDw127; IL-7R Subunit Alpha; Interleukin-7 receptor Subunit Alpha; CD127 Antigen; IL-7Ralpha; IL-7R-Alpha; IL7Ralpha; Interleukin 7 receptor Alpha Chain; Lnc-IL7R;
Species:  
Human
Source:  
HEK293
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