3 Results for "

INCB3344

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "INCB3344" in MCE Product Catalog:

30
30 Cited Publications
Cat. No.: HY-50674
CAS No.: 1262238-11-8
Target:  

CCR

INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
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1
1 Cited Publications
Cat. No.: HY-77111
CAS No.: 1285539-85-6
Target:  

CCR Drug Isomer

cis-INCB3344 is the isomer of INCB3344 (HY-50674), and can be used as an experimental control. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
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Cat. No.: HY-50674A
Target:  

CCR

Research Areas:  

Inflammation/Immunology

INCB3344 R-isomer is the R-isomer of INCB3344. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity .
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