1 Result for "

INDY (Standard)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "INDY (Standard)" in MCE Product Catalog:

Cat. No.: HY-108476R
CAS No.: 1169755-45-6
Research Areas:  

Cancer

INDY (Standard) is the analytical standard of INDY (HY-108476). This product is intended for research and analytical applications. INDY is a potent and ATP-competitive Dyrk1A and Dyrk1B inhibitor with IC50s of 0.24 μM and 0.23 μM, respectively. INDY binds in the ATP pocket of the enzyme and has a Ki value of 0.18 μM for Dyrk1A. INDY sharply reduces the self-renewal capacity of normal and tumorigenic cells in primary Glioblastoma (GBM) cell lines and neural progenitor cells .
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