2 Results for "

ITRI 90

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ITRI 90" in MCE Product Catalog:

Cat. No.: HY-171808
CAS No.: 2798907-16-9
Research Areas:  

Cancer

ITRI-90 is an orally effective androgen receptor (AR) PROTAC degrader. ITRI-90 effectively degrades full-length AR (AR-FL) and its splice variant AR-V7 proteins via the ubiquitin-proteasome system, thereby inhibiting AR transcriptional activity and the expression of its target genes, and further inducing tumor cell apoptosis. ITRI-90 can be used in research related to castration-resistant prostate cancer and Enzalutamide (HY-70002)-resistant prostate cancer .
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Cat. No.: HY-171809
CAS No.: 1240300-27-9
AR ligand 42 is a androgen receptor ligand. AR ligand 42 can be used to synthesize androgen receptor PROTAC degrader ITRI-90 (HY-171808) .
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