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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
JQAD1
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "JQAD1" in MCE Product Catalog:
2
2 Cited Publications
Research Areas:
JQAD1 is a EP300 PROTAC degrader. JQAD1 selectively targets EP300 and induces its degradation via the CRBN-dependent proteasomal pathway. JQAD1 reduces the levels of H3K27ac and the expression of MYCN. JQAD1 induces apoptosis (apoptosis) and inhibits cancer cell growth. JQAD1 exerts anti-neuroblastoma effects in vivo in a CRBN-dependent manner. JQAD1 can be used for the research of neuroblastoma [1].
Cat. No.: HY-176808
CAS No.: 2411665-33-1
Research Areas:
Thalidomide-amine-C11-acid is an E3 ligase ligand-linker conjugate which consists of
Thalidomide 5-fluoride (HY-W087383) and a linker (HY-W105740). Thalidomide-amine-C11-acid can be used to synthesize JQAD1 (HY-145765) [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
