1 Result for "

KIT/PDGFRA-IN-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KIT/PDGFRA-IN-3" in MCE Product Catalog:

Cat. No.: HY-189238
Target:  

c-Kit PDGFR

Research Areas:  

Cancer

KIT/PDGFRA-IN-3 is a KIT and PDGFRA mutant kinase inhibitor, with an IC50 of 9 nM against human PDGFRA. KIT/PDGFRA-IN-3 inhibits the kinase activity of KIT, exhibiting superior selectivity for mutant KIT over wild-type KIT. KIT/PDGFRA-IN-3 suppresses the kinase activity of PDGFRA and blocks downstream signaling pathways. KIT/PDGFRA-IN-3 can be used in studies of gastrointestinal stromal tumors .
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