1 Result for "

KP-S54

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KP-S54" in MCE Product Catalog:

Cat. No.: HY-189669
Research Areas:  

Infection

KP-S54 is an antiviral agent derived from GS-441524 (HY-103586) and also a SARS-CoV-2 Mac1 and MERS-CoV Mac1 inhibitor. KP-S54 blocks interferon-induced reversal of ADP-ribosylation, with an IC50 value of 44 nM against SARS-CoV-2 and an IC50 value of 91 nM against MERS-CoV. KP-S54 produced no detectable antiviral efficacy in a SARS-CoV-2-infected mouse model. KP-S54 can be used for research related to SARS-CoV and MERS-CoV infection .
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