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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
KT413
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "KT413" in MCE Product Catalog:
Synonyms: KT-413
Research Areas:
Zomiradomide (KT-413) is an orally active IRAK4 PROTAC degrader with a DC50 of 6 nM. Zomiradomide inhibits the NF-κB signaling pathway, while its molecular glue function mediates the degradation of Ikaros and Aiolos (with a DC50 of 1 nM for both), activates the IFN-I signaling pathway, and selectively degrades IMiD substrates. Zomiradomide inhibits cancer cell proliferation and tumor growth. Zomiradomide can be used in research related to B-cell non-Hodgkin's lymphoma and diffuse large B-cell lymphoma .
Cat. No.: HY-168313
Target:
Research Areas:
2-(2-Azaspiro[3.3]heptan-6-yl)ethanamine is the PROTAC linker of KT-413 (HY-153368) and can be used in the synthesis of PROTACs .
Cat. No.: HY-168311
CAS No.: 2654056-24-1
Research Areas:
PROTAC IRAK4 ligand-5 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs). PROTAC IRAK4 ligand-5 can be utilized for the synthesis of KT-413 (HY-153368) .
Cat. No.: HY-168312
CAS No.: 2573305-00-5
Research Areas:
Thalidomide-NH-C2-2-azaspiro[3.3]heptane is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of KT-413 (HY-153368) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
