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Kappa Immunoglobulin Light Chain

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Sirtuin (1)
By Research Areas:	Cancer (3) Inflammation/Immunology (5)

Inhibitors & Agonists

Inhibitory Antibodies

Antibodies

SIRT-IN-5	Sirtuin	Cancer
SIRT-IN-5 is a SIRT3 inhibitor, with an IC₅₀ value of 2.88 μM. SIRT-IN-5 can promote the differentiation of multiple myeloma cells, along with an increase in the expression of the differentiation antigen CD49e and human immunoglobulin light chains λ and κ .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99977

Mouse IgG1 kappa, Isotype Control Maximum Cited Publications 7 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology
Mouse IgG1 kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG1κ antibodies. Mouse IgG1 kappa, Isotype Control, by maintaining the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG1κ subtype primary antibody, eliminates false positive signals caused by non-specific binding in immunological experiments, thus playing a core role in verifying the specificity of the experiment. Mouse IgG1 kappa, Isotype Control can be applied to immunolocalization experiments in the field of cell biology, such as immunofluorescence staining and immunohistochemistry, assisting in research on protein subcellular localization and cell structure analysis, ensuring the reliability of experimental results .

HY-P990679

Rat IgG2a kappa, Isotype Control 3 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology Cancer
Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .

HY-P99978

Mouse IgG2a kappa, Isotype Control 2 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology
Mouse IgG2a kappa, Isotype Control is a negative control reagent/isotype control for mouse-derived IgG2aκ antibodies. Mouse IgG2a kappa, Isotype Control maintains the same immunoglobulin structure (including isotype, light chain, etc.) as the specific mouse IgG2aκ subtype primary antibody, thus eliminating false positive signals caused by non-specific adsorption in immunological experiments and playing a core role in verifying experimental specificity. Mouse IgG2a kappa, Isotype Control can be applied to immunolocalization experiments such as immunofluorescence staining and immunohistochemistry in the field of cell biology, assisting in protein subcellular localization, cell structure analysis, and other research to ensure the reliability of experimental results .

HY-P990120

*Anti-Rat Kappa* Immunoglobulin Light Chain Antibody (MAR 18.5)**	Inhibitory Antibodies	Inflammation/Immunology
Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) is an anti-rat **Kappa Immunoglobulin Light Chain** IgG2a monoclonal antibody. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance B cell depletion. Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can enhance T cell exhaustion after the injection of CD4 mAb (HY-P990792) and CD8 mAb (HY-P99129). Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) can be used for research on immunology .

HY-P991040

hu14.18 (K322A) Gamsitabart; M3554 Antibody	Inhibitory Antibodies	Cancer
hu14.18 (K322A) is a humanized anti-disialoganglioside GD2 monoclonal antibody that contains fully human amino acid sequences for immunoglobulin G1 heavy and kappa light chains. hu14.18 (K322A) has antibody-dependent cellular cytotoxicity (ADCC). hu14.18 (K322A) can be used for the study of high-risk neuroblastoma .

HY-P990119

*Anti-Mouse Kappa* Immunoglobulin Light Chain Antibody (HB-58)**	Inhibitory Antibodies	Inflammation/Immunology
Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) is an anti-mouse **Kappa Immunoglobulin Light Chain** IgG1 monoclonal antibody. Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) can reduce the phosphorylation levels of Src and Syk in B cells and the antigen presentation ability of B cells. Anti-Mouse Kappa Immunoglobulin Light Chain Antibody (HB-58) can be used for research on immunology .

Host:	Rabbit (2)
Reactivity:	Human (2)
Application:	IHC-P (2) ICC/IF (1) WB (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (2)
Clonality:	Monoclonal (2) Recombinant (2)
Modification:	Unmodified (2)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P82251

	Human kappa Light Chain Antibody (YA1996) HCAK1; Ig Kappa Chain C region; IGKC; Immunoglobulin InV; Km	WB, IHC-P, ICC/IF	Human
	Human kappa Light Chain Antibody (YA1996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human kappa Light Chain.

HY-P86911

	Human Kappa light chain Antibody (YA6604) Immunoglobulin Kappa variable 1D-16 Ig Kappa Chain V-I region HK146 Ig Kappa Chain V-I region HK189 Immunoglobulin Kappa constant Ig Kappa Chain C regionCurated Ig Kappa Chain C region AG Ig Kappa Chain C region CUM Ig Kappa Chain C region EU Ig Kappa Chain C region OU Ig Kappa Chain C region ROY Immunoglobulin Kappa variable 1D-16 Ig Kappa Chain V-I region HK146 Ig Kappa Chain V-I region HK189 Immunoglobulin Kappa constant Ig Kappa Chain C regionCurated Ig Kappa Chain C region AG Ig Kappa Chain C region CUM Ig Kappa Chain C region EU Ig Kappa Chain C region OU Ig Kappa Chain C region ROY Ig Kappa Chain C region TI	WB, IHC-P	Human
	Human Kappa light chain Antibody (YA6604) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human Kappa light chain.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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