5 Results for "

LAPC4

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "LAPC4" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-16079
CAS No.: 1240299-33-5
Target:  

Androgen Receptor

Research Areas:  

Cancer

AZD3514 is an orally activie and selective androgen receptor (AR) inhibitor. AZD3514 androgen-dependently and -independently inhibits AR signal. AZD351 down-regulates nuclear AR levels in human LNCaP prostate cancer cells in the absence of androgen with an pIC50 value of 5.75. AZD3514 can be used for the research of prostate cancer .
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2
2 Cited Publications
Cat. No.: HY-N7045
CAS No.: 142796-22-3
Isosilybin B is a flavonolignan. Isosilybin B can be isolated from Silybum marianum. Isosilybin B can regulate cell cycle-related proteins (e.g., reduce cyclins (D3, D1, A, E), Cdk4, Cdk2, Cdc25A), and activate Caspases (Caspase-9 and Caspase-3). Isosilybin B can promote Apoptosis, reduce androgen receptor (AR) and PSA. Isosilybin B has anticancer activity against prostate cancer .
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Cat. No.: HY-173155
Target:  

Akt

Research Areas:  

Cancer

AKT1-IN-9 (4) is a selective mutant AKT1(E17K) inhibitor, with EC50 values of 9 nM and 995 nM in LAPC4-CR and SkBr3 cells, respectively .
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Cat. No.: HY-121094
CAS No.: 927819-39-4
Target:  

Estrogen Receptor/ERR

Research Areas:  

Cancer

Androgen receptor allosteric antagonist 1(compound D36)is a a llosteric, competitive androgen receptor (AR) antagonist with the Ki of 9 μM. Androgen receptor allosteric antagonist 1 inhibits R1881-mediated transcription and proliferation and can be used for study of prostate cancer .
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Cat. No.: HY-W054427
CAS No.: 70842-04-5
Target:  

Parasite

Research Areas:  

Infection Metabolic Disease

Ro 13-3978 is an orally active antischistosomal agent. Ro 13-3978 exhibits excellent in vivo antischistosomal activity against juvenile and adult Schistosoma mansoni infections. Ro 13-3978 shows no in vivo activity against E. caproni and F. hepatica. Ro 13-3978 blocks dihydrotestosterone-induced proliferation of androgen-dependent cells. Ro 13-3978 can be used in research related to schistosomiasis .
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