1 Result for "

LDR102

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LDR102" in MCE Product Catalog:

Cat. No.: HY-162640
CAS No.: 3053223-31-4
Target:  

ROR

연구분야:  

Cancer

LDR102 (Compound 19h) is an inhibitor for receptor tyrosine kinase-like orphan receptor 1 (ROR 1) with Ki of 0.10 μM. LDR102 inhibits proliferation of cancer cells H1975, A549 and MDA-MB-231, with IC50 of 0.36 μM, 1.37 μM and 0.47 μM. LDR102 exhibits antitumor efficacy in mice and good pharmacokinetic characteristics in rat models .
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