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Results for "

LEFTY1

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Fluorescent Dyes

1

Biochemical Assay Reagents

1

Oligonucleotides

1

GMP Molecules

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS07585
    LEFTY1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    LEFTY1 Human Pre-designed siRNA Set A contains three designed siRNAs for LEFTY1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    LEFTY1 Human Pre-designed siRNA Set A
    LEFTY1 Human Pre-designed siRNA Set A
  • HY-10321G
    PD173074

    		FGFR TGF-beta/Smad Cancer
    PD173074 GMP is PD173074 (HY-10321) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. PD173074 is an orally active FGFR inhibitor that targets the transphosphorylation of FGFR1 and FGFR2 and blocks the FGF signaling pathway. By reducing the phosphorylation level of SMAD2 and altering the expression of Nodal/Activin target genes, PD173074 eliminates endothelial differentiation potential, thereby inhibiting the formation of capillary-like structures. PD173074 blocks the proliferation and colony formation of tumor cells and increases intratumoral cell apoptosis. PD173074 successfully reverses FGF-2-induced chemoresistance to enhance the effect of cisplatin (HY-17394) in small cell lung cancer models. PD173074 can be applied to research related to critical limb ischemia and small cell lung cancer [1] .
    PD173074

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