1 Result for "

LEI106

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LEI106" in MCE Product Catalog:

Cat. No.: HY-124314
CAS No.: 1620582-23-1
Target:  

MAGL DAGL

Research Areas:  

Metabolic Disease

LEI-106 is a dual ABHD6 and DAGL-α inhibitor, with a Ki of 0.8 μM for ABHD6, and an IC50 of 18 nM and a Ki of 0.7 μM for DAGL-α. LEI-106 blocks the synthesis of 2-arachidonoylglycerol, reduces the level of endothelial cell-derived 2-arachidonoylglycerol, without altering the levels of cannabinoids and diacylglycerol. LEI-106 is applicable to research related to diet-induced obesity and metabolic syndrome .
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