Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
123 Results for "
LRP
" in MedChemExpress (MCE) Product Catalog:
Products (123)
123 Results for "LRP" in MCE Product Catalog:
52
52 Publications Verification
Cat. No.: HY-17439
CAS No.: 55721-31-8
Synonyms: Salinomycin sodium; Sodium salinomycin
Domaines de recherche:
Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt shows selective activity against human cancer stem cells .
52
52 Publications Verification
Synonyms: Procoxacin
Domaines de recherche:
Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, selectively inhibits the growth of gram-positive bacteria. Salinomycin is a potent inhibitor of Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation. Salinomycin shows selective activity against human cancer stem cells .
15
15 Cited Publications
Domaines de recherche:
HLY78, a Lycorine (HY-N0288) derivative, is a potent activator of the Wnt/β-catenin signaling pathway. HLY78 targets the DIX domain of Axin and promotes the Axin-LRP6 (lipoprotein receptor-related protein 6) association, thus promoting LRP6 phosphorylation and Wnt signal transduction. HLY78 can be used for subarachnoid hemorrhage (SAH) research .
5
5 Cited Publications
Target:
Domaines de recherche:
TM5275 sodium can inhibit the interaction between PAI-1 and LRP1.
3
3 Cited Publications
Cat. No.: HY-P702520
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: A2MR; Alpha-2-Macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5
3
Target:
Domaines de recherche:
CPA inhibitor (Compound 5) (Carboxypeptidase inhibitor) is an orally active competitive carboxypeptidase A (CPA) inhibitor with a Ki value of 0.32 μM. CPA inhibitor blocks the activity of carboxypeptidase A3 (CPA3). CPA activator activates the Wnt/Lrp6/β-catenin signaling pathway. CPA inhibitor reduces epithelial damage. CPA inhibitor is applicable to research related to inflammatory bowel disease, including ulcerative colitis and Crohn's disease .
1
1 Cited Publications
Cat. No.: HY-P704765
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: A2MR; Alpha-2-Macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5
1
1 Cited Publications
Cat. No.: HY-P704766
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: A2MR; Alpha-2-Macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5
1
1 Cited Publications
Cat. No.: HY-P704767
Pureté: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: A2MR; Alpha-2-Macroglobulin Receptor; APOER; APR; CD91; LRP1 Cluster II; LRP-1 Cluster II; LRP1; TGFBR5
Target:
Domaines de recherche:
Gallocyanine chloride is a synthetic blue dyestuff that can be used as a potential agent for the research of Alzheimer's disease and related neurodegenerative tauopathies. Gallocyanine chloride inhibits DKK1/LRP6 interaction (IC50=6.38 μM), activates Wnt signaling pathway, and causes β-catenin accumulation. Gallocyanine chloride exhibits anti-metastasis, anti-inflammatory and anti-fibrosis activities. Gallocyanine chloride can be used as a fluorescent probe for detection of superoxide anion radicals .
Cat. No.: HY-P10502
CAS No.: 2378836-93-0
Cat. No.: HY-P990202
Target:
Domaines de recherche:
Cat. No.: HY-P10502A
Cat. No.: HY-172699
Cat. No.: HY-P4130
CAS No.: 1180485-56-6
Cat. No.: HY-17439R
CAS No.: 55721-31-8
Synonyms: Salinomycin sodium (Standard); Sodium salinomycin (Standard)
Domaines de recherche:
Salinomycin (sodium salt) (Standard) is the analytical standard of Salinomycin (sodium salt). This product is intended for research and analytical applications. Salinomycin sodium salt (Salinomycin sodium), an antibiotic potassium ionophore, is a potent inhibitor of Wnt/β-catenin signaling. Salinomycin sodium salt (Salinomycin sodium) acts on the Wnt/Fzd/LRP complex, blocks Wnt-induced LRP6 phosphorylation, and causes degradation of the LRP6 protein. Salinomycin sodium salt (Salinomycin sodium) shows selective activity against human cancer stem cells .
Cat. No.: HY-RS23105
Target:
Domaines de recherche:
Lrp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Lrp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
BMD4503-2 is a quinoxaline derivative with inhibitory activity against LRP5/6-sclerostin interactions. BMD4503-2 restores the activity of the Wnt/β-catenin signaling pathway by competitively binding to the LRP5/6-sclerostin complex. BMD4503-2 can be used in the study of Wnt signaling pathways in bone development, maintenance and osteoporosis .
Cat. No.: HY-RS16670
Target:
Domaines de recherche:
Lrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
