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LY2228820 dimesylate

" in MedChemExpress (MCE) Product Catalog:
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Cat. No.: HY-13241
CAS No.: 862507-23-1
Purity:  99.94%
Synonyms: LY2228820 dimesylate
Research Areas:  

Inflammation/Immunology Cancer

Ralimetinib dimesylate (LY2228820 dimesylate) is a selective, ATP-competitive inhibitor of p38 MAPK α/β with IC50s of 5.3 and 3.2 nM, respectively. Ralimetinib (LY2228820) selectively inhibits phosphorylation of MK2 (Thr334), with no effect on phosphorylation of p38a MAPK, JNK, ERK1/2, c-Jun, ATF2, or c-Myc.
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