28 Results for "

Leucine Aminopeptidase

" in MedChemExpress (MCE) Product Catalog:
Products (28)

28 Results for "Leucine Aminopeptidase" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-113952
CAS No.: 13434-13-4
Purity:  98.37%
Synonyms: (-)-Actinonin
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities .
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3
3 Cited Publications
Cat. No.: HY-114336
CAS No.: 11029-12-2
Enocyanin is an anthocyanin extracted from grapes. Enocyanin shows inhibitory effect on the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity .
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1
1 Cited Publications
Cat. No.: HY-115194
CAS No.: 100938-10-1
Purity:  98%
Research Areas:  

Infection

Amastatin hydrochloride is a slow, tight binding, competitive aminopeptidase (AP) inhibitor with Ki values of 0.26 nM, 30 nM, 52 nM for Aeromonas aminopeptidase, cytosolic leucine aminopeptidase, microsomal aminopeptidase .
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Cat. No.: HY-137844
CAS No.: 62480-44-8
Purity:  99.98%
Synonyms: Leu-AMC hydrochloride
L-Leucine-7-amido-4-methylcoumarin (Leu-AMC) hydrochloride is a bright blue fluorogenic peptidyl substrate for LAP3 (leucine aminopeptidase). L-Leucine-7-amido-4-methylcoumarin hydrochloride can be used for leucine aminopeptidase inhibition assays in vitro .
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Cat. No.: HY-W011911
CAS No.: 4178-93-2
L-Leucyl-4-nitroanilide is a chromogenic substrate suitable for activity assays of leucine aminopeptidase, and it can be used in studies related to the enzymatic properties of aminopeptidases .
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Cat. No.: HY-W015876
CAS No.: 7533-40-6
Synonyms: (+)-Leucinol
Target:  

Aminopeptidase

Research Areas:  

Others

L-Leucinol ((+)-Leucinol) is a competitive aminopeptidase inhibitor with a Ki value of 17 μM. As a dietary intake inhibitor, L-Leucinol reduces the basal dietary leucine intake in rats via microinjection into the rat anterior piriform cortex .
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Cat. No.: HY-137872
CAS No.: 16010-98-3
Purity:  99.97%
L-Leucyl-4-nitroanilide hydrochloride is a chromogenic substrate suitable for activity assays of leucine aminopeptidase, and it can be used in studies related to the enzymatic properties of aminopeptidases .
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Cat. No.: HY-P2648
CAS No.: 70968-04-6
Synonyms: N-Succinyl-AAPL-p-nitroanilide
Target:  

Aminopeptidase

Research Areas:  

Endocrinology

Suc-Ala-Ala-Pro-Leu-pNA (N-Succinyl-AAPL-p-nitroanilide) is a tripeptidyl p-nitroanilide substrate that can be catalytically hydrolyzed by acyl amidase-like leucine aminopeptidase in seminal plasma. Amastatin (HY-129298) and Actinonin (HY-113952) exert potent inhibitory effects on this hydrolytic activity. Suc-Ala-Ala-Pro-Leu-pNA can be used for the research of diseases such as azoospermia .
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Cat. No.: HY-P2928
CAS No.: 37288-67-8
Research Areas:  

Others

Aeromonas proteolytica aminopeptidase is an aminopeptidase from Aeromonas proteolytica. Aeromonas proteolytica aminopeptidase can function as an esterase. Aeromonas proteolytica aminopeptidase can catalyze the hydrolysis of L-leucine ethyl ester (L-Leu-OEt) with a Km of 700 µM .
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Cat. No.: HY-P11334
CAS No.: 850131-23-6
Cyanostatin B, a cyanobacterial lipopeptide, is a leucine aminopeptidase M (LAP) inhibitor (IC50 = 12 ng/mL). Cyanostatin B is a weak inhibitor of protein phosphatase (PP2A) and also exhibits weak inhibitory activity against angiotensin-converting enzyme (ACE), with an IC50 value of 130 μg/mL. Cyanostatin B demonstrates both cytotoxic and genotoxic effects on human hepatocytes, although non-toxic to Artemia salina. Cyanostatin B inhibits the proliferation of HepG2 cells, induces DNA single-strand breaks, and causes genomic instability. .
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Cat. No.: HY-121123
CAS No.: 42381-05-5
Purity:  ≥97.0%
Synonyms: 2-Aminoadamantane-2-carboxylic acid
Target:  

Aminopeptidase

Research Areas:  

Cancer

Adamantanine (2-Aminoadamantane-2-carboxylic acid) inhibits the transport of methionine (Ki is 0.76 mM) and leucine into Ehrlich ascites carcinoma cells. Adamantanine inhibits proliferation of P388 lymphocytic leukemia cells with an IC50 of >1 mM. Adamantanine inhibits the leucine aminopeptidase with an I/S0.5 of 10.5 .
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Cat. No.: HY-W795259
CAS No.: 66254-56-6
Target:  

MMP

L-Val-P is a potent leucine aminopeptidase (LAP) inhibitor with a Ki of 0.15 μM. L-Val-P is promising for research of HIV infection, inflammation, eye lens cataract and cancer .
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Cat. No.: HY-137946
CAS No.: 4467-68-9
Target:  

Aminopeptidase

Research Areas:  

Others

L-Leucine 4-methoxy-β-naphthylamide hydrochloride is an aminopeptidase M and leucine aminopeptidase substrate .
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Cat. No.: HY-E70964A
Target:  

Aminopeptidase

Research Areas:  

Metabolic Disease

Leucine Aminopeptidase, Porcine (EC 3.4.11.1) is a proteolytic enzyme which hydrolyzes the peptide bond adjacent to a free amino group. Leucine Aminopeptidase, Porcine (EC 3.4.11.1) rapidly catalyzes the hydrolysis of leucine containing peptides and also catalyzes the hydrolytic release of other amino acids located at the N-terminal end of various peptides and proteins.
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Cat. No.: HY-E70964
Target:  

Aminopeptidase

Research Areas:  

Metabolic Disease

Leucine Aminopeptidase(microsomal), Porcine (EC 3.4.11.2) is an enzyme that preferentially catalyze the hydrolysis of leucine residues at the N-terminus of peptides and proteins.
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Cat. No.: HY-125341
CAS No.: 1135249-50-1
Microginin 527 is a linear cyanobacterial peptide with potent angiotensin-converting enzyme (ACE) inhibitory activity. Microginin 527 also exhibits inhibitory effects on protein phosphatases and leucine aminopeptidase. With an IC50 value of 31 μM, Microginin 527 is the most active component in this class of compounds .
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Cat. No.: HY-113952R
CAS No.: 13434-13-4
Synonyms: (-)-Actinonin (Standard)
Actinonin (Standard) is the analytical standard of Actinonin. This product is intended for research and analytical applications. Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase. Actinonin is a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. Actinonin also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin is an apoptosis inducer. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].
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Cat. No.: HY-107761
CAS No.: 148473-36-3
Target:  

Neurotensin Receptor

Research Areas:  

Neurological Disease

JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC50 values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium .
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Cat. No.: HY-P702168
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Probable cytosol Aminopeptidase; 3.4.11.1; Leucine Aminopeptidase; LAP; Leucyl Aminopeptidase; 3.4.11.10; pepA
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-P702169
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Probable cytosol Aminopeptidase; 3.4.11.1; Leucine Aminopeptidase; LAP; Leucyl Aminopeptidase; 3.4.11.11; pepA
Species:  
Others
Source:  
E. coli
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