Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Lovastatin
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Lovastatin" in MCE Product Catalog:
41
5
1
1 Cited Publications
Synonyms: Antibiotic MB 530A; Lovastatin diol lactone
Target:
Research Areas:
Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.
Synonyms: Mevinolinic acid sodium
Target:
Research Areas:
Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM .
Cat. No.: HY-N0504R
CAS No.: 75330-75-5
Synonyms: Mevinolin (Standard)
Cat. No.: HY-122439
CAS No.: 75225-51-3
Synonyms: Mevinolinic acid; MSD803
Cat. No.: HY-169818
CAS No.: 96497-73-3
Target:
Research Areas:
Keto lovastatin is an impurity of Lovastatin (HY-N0504) with antibacterial activity. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol .
Cat. No.: HY-N0504S2
CAS No.: 1002345-93-8
Synonyms: Mevinolin-d3
Cat. No.: HY-N0504S1
CAS No.: 2508138-69-8
Synonyms: Mevinolin-d9 (epimer mixture)
Cat. No.: HY-137371R
CAS No.: 148409-20-5
Lovastatin hydroxy acid (sodium) (Standard) is the analytical standard of Lovastatin hydroxy acid (sodium). This product is intended for research and analytical applications. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM .
Cat. No.: HY-Z8472
CAS No.: 77517-29-4
Synonyms: Lovastatin EP impurity E; 4a,5-Dihydromevinolin
Category:
Cat. No.: HY-18714
CAS No.: 329059-55-4
BRD7116 is a cell-non-autonomous inhibitor of leukemic stem cells (LSCs). BRD7116, without directly contacting LSCs, can inhibit LSCs merely by altering the microenvironment. BRD7116 also has any cell-autonomous effects on LSCs and induces transcriptional changes consistent with myeloid differentiation. BRD7116 can be used for the study of leukemia .
Cat. No.: HY-N0504S
CAS No.: 1330264-51-1
Cat. No.: HY-123672R
CAS No.: 75225-50-2
Synonyms: Mevinolinic acid sodium (Standard)
Research Areas:
Lovastatin hydroxy acid (sodium) (Standard) is the analytical standard of Lovastatin hydroxy acid (sodium). This product is intended for research and analytical applications. Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a highly potent inhibitor of HMG-CoA reductase with a Ki of 0.6 nM .
Cat. No.: HY-143802S
CAS No.: 2244401-55-4
Cat. No.: HY-117219
CAS No.: 136209-43-3
Research Areas:
SKF 104976 is a 3,2-carboxylic acid derivative with potent 14-alpha-demethylase (14 alpha DM) inhibitory activity. SKF 104976 inhibited 14 alpha DM activity by 50% at 2 nM in Hep G2 cell extracts. SKF 104976 inhibited the incorporation of [14C]acetate into cholesterol in intact cells at similar concentrations, accompanied by accumulation of lanosterol, and resulted in a 40-70% decrease in 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) activity. SKF 104976 did not affect the uptake and degradation of low-density lipoprotein in Hep G2 cells, indicating that HMGR and low-density lipoprotein receptor activities are not coordinately regulated under these conditions. The inhibitory effect of SKF 104976 on HMGR activity remained unchanged even when the flux of carbon units in the sterol synthesis pathway was reduced by 80%. SKF 104976 did not inhibit HMGR activity under conditions where sterol synthesis was almost completely blocked by lovastatin .
Cat. No.: HY-123672S
CAS No.: 1217528-38-5
Synonyms: (rel)-Mevinolinic acid-d3 sodium
Research Areas:
(rel)-Lovastatin hydroxy acid-d3 ((rel)-Mevinolinic acid-d3) sodium is the deuterium labeled (rel)-Lovastatin hydroxy acid sodium.
Acetyllovastatin, a acetate of Lovastatin, presentes a moderate inhibitory effect against the enzyme acetylcholinesterase with an IC50 of 79 μg/mL. Lovastatin has been found to display antifungal activity, and suppresses proliferation of a number of transformed cell lines .
Cat. No.: HY-E71587
Target:
Research Areas:
2-Methylbutanoate polyketide synthase (EC 2.3.1.244) is a polyketide synthase that forms the (S)-2-methylbutyrate side chain during the biosynthesis of lovastatin in the filamentous fungus Aspergillus terreus.
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
