1. Metabolic Enzyme/Protease
    Autophagy
  2. HMG-CoA Reductase (HMGCR)
    Autophagy
  3. Monacolin J

Monacolin J (Synonyms: Antibiotic MB 530A; Lovastatin diol lactone)

Cat. No.: HY-104051
Handling Instructions

Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.

For research use only. We do not sell to patients.

Monacolin J Chemical Structure

Monacolin J Chemical Structure

CAS No. : 79952-42-4

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Description

Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.

IC50 & Target

HMG-CoA reductase[1]

In Vitro

Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase. Na salt of Monacolin J causes 50% inhibition on reductase at 1.2 μg/mL[1].

Molecular Weight

320.42

Formula

C₁₉H₂₈O₄

CAS No.

79952-42-4

SMILES
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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Monacolin J
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