1. Metabolic Enzyme/Protease
  2. HMG-CoA Reductase (HMGCR) Drug Metabolite
  3. Lovastatin acid

Lovastatin acid  (Synonyms: Mevinolinic acid; MSD803)

Cat. No.: HY-122439
Handling Instructions

Lovastatin acid (Mevinolinic acid), an active metabolite of Lovastatin, is a potent competitive HMG-CoA reductase inhibitor with a Ki of 0.6 nM.

For research use only. We do not sell to patients.

Lovastatin acid Chemical Structure

Lovastatin acid Chemical Structure

CAS No. : 75225-51-3

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Description

Lovastatin acid (Mevinolinic acid), an active metabolite of Lovastatin, is a potent competitive HMG-CoA reductase inhibitor with a Ki of 0.6 nM[1].

IC50 & Target

Ki: 0.6 nM (HMG-CoA reductase)[1]

Molecular Weight

422.55

Formula

C24H38O6

CAS No.
SMILES

O=C(C[C@@H](C[C@@H](CC[C@H]1[C@H](C=CC2=C[C@@H](C[C@@H]([C@]12[H])OC([C@H](CC)C)=O)C)C)O)O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Lovastatin acid Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Lovastatin acid
Cat. No.:
HY-122439
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