1 Result for "

Lys352

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Lys352" in MCE Product Catalog:

Cat. No.: HY-149388
CAS No.: 2954795-29-8
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Anticancer agent 139 (Compound 6h) has potent anticancer activity. Anticancer agent 139 displayed a π–cationic interaction with the residue Lys352 of Tublin. Anticancer agent 139 has good anticancer activity against SNB-19, OVCAR-8, and NCI-H40 with PGIs of 86.61, 85.26, and 75.99, respectively. Anticancer agent 139 also has moderate anticancer activity against HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 with PGIs of 67.55, 65.46, 59.09, 59.02, 57.88, 56.88, 56.53, 56.4, and 51.88 respectively .
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