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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
Lys352
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "Lys352" in MCE Product Catalog:
Cat. No.: HY-149388
CAS No.: 2954795-29-8
Target:
Research Areas:
Anticancer agent 139 (Compound 6h) has potent anticancer activity. Anticancer agent 139 displayed a π–cationic interaction with the residue Lys352 of Tublin. Anticancer agent 139 has good anticancer activity against SNB-19, OVCAR-8, and NCI-H40 with PGIs of 86.61, 85.26, and 75.99, respectively. Anticancer agent 139 also has moderate anticancer activity against HOP-62, SNB-75, ACHN, NCI/ADR-RES, 786-O, A549/ATCC, HCT-116, and MDA-MB-231 with PGIs of 67.55, 65.46, 59.09, 59.02, 57.88, 56.88, 56.53, 56.4, and 51.88 respectively .
Cat. No.: HY-189398
Target:
Research Areas:
Tubulin polymerization-IN-94 is a tubulin polymerization inhibitor. Tubulin polymerization-IN-94 inhibits tubulin polymerization, forms a hydrogen bond with β-Asn349, and exhibits π-stacking with β-Lys352. Tubulin polymerization-IN-94 shows potent antiproliferative activity against multiple cancer cell lines. Tubulin polymerization-IN-94 induces G2/M cell cycle arrest, apoptosis, and disruption of the microtubule network. Tubulin polymerization-IN-94 can be used in research related to cervical cancer, gastric cancer, and breast cancer .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
