1 Result for "

M475271

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "M475271" in MCE Product Catalog:

Cat. No.: HY-13561
CAS No.: 476159-98-5
Purity:  99.89%
Synonyms: M475271
Target:  

Src Apoptosis

Research Areas:  

Cancer

AZM475271 (M475271) is an orally active and selective Src kinase inhibitor. AZM475271 inhibits phosphorylation of c-Src kinase, Lck, c-yes (IC50s = 0.01, 0.03, 0.08 μM, respectively). AZM475271 induces apoptosis. AZM475271 reduces tumor cell proliferation and migration in vitro and in vivo, and reduces microvessel density (MVD). AZM475271 inhibits tumor growth and metastasis. AZM475271 sensitizes tumor cells to the cytotoxic effects of Gemcitabine (HY-17026) .
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