1 Result for "

MK3697

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MK3697" in MCE Product Catalog:

Cat. No.: HY-12301
CAS No.: 1224846-01-8
Purity:  98.83%
Research Areas:  

Neurological Disease

MK-3697 is an orally active orexin 2 receptor (OX2R) antagonist, with an IC50 value of 16 nM and a Ki value of 1.1 nM against human OX2R. MK-3697 blocks the wake-promoting OX2R signaling pathway, reduces active wake time, and increases slow-wave sleep and rapid eye movement sleep time in mice, rats and dogs. MK-3697 can be used for research on insomnia .
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