1 Result for "

MM144

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MM144" in MCE Product Catalog:

8
8 Cited Publications
Cat. No.: HY-19322B
CAS No.: 1820565-69-2
Synonyms: LGH447 dihydrochloride
Target:  

Pim Apoptosis

Research Areas:  

Cancer

PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride induces apoptosis .
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