1 Result for "

MRK560

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MRK560" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-14174
CAS No.: 677772-84-8
Purity:  99.51%
Target:  

γ-secretase

Research Areas:  

Neurological Disease Cancer

MRK-560, a chemical probe, is an orally active, brain barrier-penetrated γ-Secretase inhibitor, reducing Aβ peptide in rat brain and cerebrospinal fluid. MRK-560 decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL) .
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