1 Result for "

Multitarget AD-IN-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Multitarget AD-IN-7" in MCE Product Catalog:

Cat. No.: HY-182788
CAS No.: 3113741-59-3
Research Areas:  

Neurological Disease

Multitarget AD-IN-7 is an orally active multi-target anti-AD compound. Multitarget AD-IN-7 exhibits inhibitory activity against GSK-3β and GSK-3α (IC50 = 0.66, 0.83 nM). Multitarget AD-IN-7 upregulates the expression of p-GSK-3β-Ser9, inhibits the phosphorylation of tau-Ser396, targets 1-42, chelates pathogenic metal ions, scavenges ABTS•+, upregulates the expression of β-catenin and neurogenesis biomarkers, and promotes neurite outgrowth. Multitarget AD-IN-7 improves motor ability in Alzheimer's disease zebrafish. Multitarget AD-IN-7 is applicable to research related to Alzheimer's disease .
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