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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NCI H187
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NCI H187" in MCE Product Catalog:
Cat. No.: HY-W779529
CAS No.: 25633-33-4
Synonyms: 2'-Acetylneriifolin
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Cerberin is a cardiac glycoside that has been found in C. odollam and has cytotoxic and cardiac modulatory activities. It is cytotoxic to KB and NCI H187 cancer cells (IC50s=1.92 and 1.24 μg/mL).1 Cerberin inhibits Na+/K+-ATPase, increasing intracellular sodium levels and action potential duration in cardiac cells.
Cat. No.: HY-145379
CAS No.: 3039491-16-9
Category:
Infection Quinones Monophenols Anthraquinones Phenols Endogenous metabolite Disease Research Fields
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Cat. No.: HY-N12232
CAS No.: 108073-63-8
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Cat. No.: HY-N15652
CAS No.: 30270-17-8
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Cat. No.: HY-N12230
CAS No.: 1418291-70-9
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Cat. No.: HY-N8470
CAS No.: 54526-94-2
Synonyms: NSC 204855; U 40615
Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC50s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC50=2.19 μM).
Cat. No.: HY-N7302
CAS No.: 1801750-22-0
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Cat. No.: HY-N12231
CAS No.: 75139-38-7
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Cat. No.: HY-N21796
CAS No.: 1362114-29-1
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Cat. No.: HY-178724
CAS No.: 1179374-63-0
Mollicellin K is a depsidone that can be isolated from the fungus Chaetomium brasiliense. Mollicellin K exhibits antimicrobial activity against Myobacterium tuberculosis, antimalarial activity (IC50 = 1.2 μM) against Plasmodium falciparum as well as antifungal property (IC50 = 1.2 μM) against Candida albicans. Mollicellin K is cytotoxic against KB (IC50 = 1.9 μM), BC1 (IC50 = 6.8 μM), NCI-H187 (IC50 = 0.35 μM), and five cholangiocarcinoma cell lines. Mollicellin K also has an MIC of 12.5 μM for tuberculosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
