3039491-16-9
Chemical Structure
Miaosporone A
- CAS No.: 3039491-16-9
- Formula:C19H18O5
- Molecular Weight:326.34
IUPAC Name: 5-fluoro-2-(methylthio)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
InChIKey: IDOWIDKROXUFMT-NRXGSXMXSA-N
SMILES: O[C@]12CCC(C(C3=C(C4=O)C=CC=C3O)=O)=C4[C@@]1([H])[C@H](O)C=C(C)C2
Biological Activity: Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC50 values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells[1].
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Miaosporone A | Miaosporone A, an angucyclic quinone, exhibits antimalarial activity against Plasmodium falciparum K1 and antibacterial activity against Mycobacterium tuberculosis with respective IC50 values of 2.5 and 2.4 μM and displays cytotoxic activities against both cancerous (MCF-7 and NCI-H187) and nonmalignant (Vero) cells. | |||||||||||||||||||||
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Keywords
