1 Result for "

NNC-112

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NNC-112" in MCE Product Catalog:

Cat. No.: HY-165450
CAS No.: 125341-24-4
NNC-112 is a dopamine D1 receptor antagonist with a Ki of 0.18 nM for rat D1R and a Ki of 18 nM for 5-HT2. NNC-112 competitively inhibits [ 3H]SCH 23390 binding and blocks dopamine-stimulated adenylate cyclase. NNC-112 blocks D1 receptor-mediated rotational behavior in 6-OHDA-lesioned rats. NNC-112 can serve as a C11-labeled radioligand ([11C] NNC 112) for positron emission tomography imaging. NNC-112 can be used for research on schizophrenia and hypertension .
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