Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
NTSR1
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "NTSR1" in MCE Product Catalog:
1
1 Cited Publications
Target:
Research Areas:
SBI-553 is a potent and brain penetrant NTR1 allosteric modulator, with an EC50 of 0.34 μM [1] .
Cat. No.: HY-164795A
CAS No.: 2772746-58-2
Research Areas:
SBI-810 hydrochloride is a blood-brain barrier-permeable NTSR1 modulator. SBI-810 hydrochloride promotes the recruitment of β-arrestin-2 to NTSR1 and antagonizes NTSR1-mediated Gq activation. SBI-810 hydrochloride inhibits excitatory synaptic transmission, NMDA receptor and extracellular signal-regulated kinase (ERK) signaling in spinal nociceptive neurons, reduces surface expression of Nav1.7 and action potential firing in primary sensory neurons, and attenuates C-fiber responses. SBI-810 hydrochloride effectively alleviates acute and chronic pain in various rodent models through peripheral and central modulation. SBI-810 hydrochloride is applicable to research related to multiple pain disorders [1] .
Cat. No.: HY-164795
CAS No.: 1849603-79-7
Research Areas:
SBI-810 is a blood-brain barrier-permeable NTSR1 modulator. SBI-810 promotes the recruitment of β-arrestin-2 to NTSR1 and antagonizes NTSR1-mediated Gq activation. SBI-810 inhibits excitatory synaptic transmission, NMDA receptor and extracellular signal-regulated kinase (ERK) signaling in spinal nociceptive neurons, reduces surface expression of Nav1.7 and action potential firing in primary sensory neurons, and attenuates C-fiber responses. SBI-810 effectively alleviates acute and chronic pain in various rodent models through peripheral and central modulation. SBI-810 is applicable to research related to multiple pain disorders [1] .
Cat. No.: HY-RS09638
Research Areas:
NTSR1 Human Pre-designed siRNA Set A contains three designed siRNAs for NTSR1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09639
Research Areas:
Ntsr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ntsr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS09640
Research Areas:
Ntsr1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ntsr1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10698
CAS No.: 1801681-81-1
Target:
Research Areas:
Cat. No.: HY-182551
CAS No.: 1623019-77-1
Target:
Research Areas:
SR-12062 is a Neurotensin receptor 1 (NTSR1) full agonist that modulates NTSR1 to trigger intracellular Ca 2+ mobilization. SR-12062 can be used for the research of schizophrenia, parkinson’s disease, drug addiction [1].
Cat. No.: HY-P705672
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NT-R-1; NTR1; High-affinity levocabastine-insensitive neurotensin receptor; NTRH
Species:
Source:
Cat. No.: HY-153709
CAS No.: 1613265-38-5
Synonyms: IPN-01087
Target:
Research Areas:
Zalsenertant tetraxetan (IPN-01087) is a DOTA-conjugated antagonist of the neurohypophyseal hormone receptor subtype 1 (NTSR1). Zalsenertant tetraxetan is labeled with the radioactive isotope Lu-177 (177Lu), which can be used for molecular imaging to identify potential responders. Zalsenertant tetraxetan can be used in the radiotherapy research of solid tumors [1].
Cat. No.: HY-P11845
Research Areas:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
