7 Results for "

Niflumic Acid

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Niflumic Acid" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-B0493
CAS No.: 4394-00-7
Target:  

Chloride Channel COX

Research Areas:  

Inflammation/Immunology Cancer

Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-103370
CAS No.: 66898-62-2
Purity:  99.67%
Synonyms: BA 7602-06
Target:  

Chloride Channel

Research Areas:  

Inflammation/Immunology

Talniflumate (BA 7602-06) is the proagent of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase . Talniflumate is an orally active Ca 2+-activated Cl - channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome .
loading...
    loading...
Cat. No.: HY-B0493R
CAS No.: 4394-00-7
Niflumic acid (Standard) is the analytical standard of Niflumic acid. This product is intended for research and analytical applications. Niflumic acid is a calcium-activated chloride channel blocker and COX-2 inhibitor with the IC50 value of 100 nM. Niflumic acid induces apoptosis through caspase-8/Bid/Bax pathway in lung cancer cells. Niflumic acide exhibits anti-tumor activity by affecting the expression of ERK1/2 and the activity of MMP2 and MMP9. Niflumic acid has orally bioactivity. Niflumic acid acts on rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-B0493S1
CAS No.: 1325559-33-8
Niflumic acid- 13C6 is the 13C6 labeled Niflumic acid. Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
loading...
    loading...
Cat. No.: HY-B0493S
CAS No.: 1794811-58-7
Niflumic Acid-d5 is the deuterium labeled Niflumic acid. Niflumic acid, a Ca2+-activated Cl- channel blocker, is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis .
loading...
    loading...
Cat. No.: HY-103370R
CAS No.: 66898-62-2
Synonyms: BA 7602-06 (Standard)
Talniflumate (Standard) is the analytical standard of Talniflumate. This product is intended for research and analytical applications. Talniflumate (BA 7602-06) is the proagent of Niflumic acid (HY-B0493), exerting its activity in the body through conversion to niflumic acid by esterase . Talniflumate is an orally active Ca2+-activated Cl- channel (CaCC) blocker. Talniflumate can be used as an analgesic and anti-inflammatory agent in cystic fibrosis mouse model of distal intestinal obstructive syndrome .
loading...
    loading...
Cat. No.: HY-17488R
CAS No.: 65847-85-0
Synonyms: UP 164 (Standard)
Morniflumate (Standard) is the analytical standard of Morniflumate. This product is intended for research and analytical applications. Morniflumate (UP 164) is an orally active nonsteroidal anti-inflammatory agent, the β-morpholinoethyl ester of Niflumic acid (HY-B0493). Morniflumate can be used in the study of inflammatory diseases such as osteoarthritis, painful musculoskeletal disorders and soft tissue inflammation.
loading...
    loading...