1 Result for "

OPB3206

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "OPB3206" in MCE Product Catalog:

Cat. No.: HY-171776
CAS No.: 166245-54-1
Target:  

MMP

Research Areas:  

Cancer

OPB-3206 is a selective matrix metalloproteinase (MMP) inhibitor. OPB-3206 inhibits interstitial collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9) and stromelysin with IC50 values of 7×10 -7 M, 5×10 -6 M, 5×10 -7 M and 2×10 -6 M, respectively. OPB-3206 reversibly binds to the zinc-binding region of MMPs, preventing the activation of MMP-9 and reducing extracellular matrix degradation to inhibit tumor lung metastasis. OPB-3206 is promising for research of lung metastasis of osteosarcoma .
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