1 Result for "

Opitor0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Opitor0" in MCE Product Catalog:

Cat. No.: HY-177306
Target:  

Dynamin Apoptosis

Research Areas:  

Cancer

Opitor-0 is a OPA1 GTPase inhibitor with an IC50 of 3.0 μM. Opitor-0 disrupts mitochondrial cristae structure and respiratory efficiency, induces mitochondrial fragmentation, enhances cBID-mediated cytochrome c release, and restores the sensitivity of triple-negative breast cancer (TNBC) cells to ABT-737 (HY-50907). Opitor-0 selectively reduces the migration and proliferation capacities of metastatic breast cancer cells, and induces cell death and apoptosis. Opitor-0 can be used in studies related to metastatic breast cancer and triple-negative breast cancer .
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