1 Result for "

Org 274178-0

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Org 274178-0" in MCE Product Catalog:

Cat. No.: HY-153213A
Target:  

TSH Receptor

Research Areas:  

Endocrinology

Org 274178-0 is a selective thyroid-stimulating hormone receptor (TSHR) antagonist with a pIC50 value for TSHR is 5.03. Org 274178-0 inhibits the activation of cAMP signaling pathway and phospholipase C (PLC) signaling pathway mediated by thyroid-stimulating hormone (TSH) and TSH receptor-stimulating immunoglobulins (TSIs). Org 274178-0 is promising for research of Graves’ disease and Graves’ ophthalmopathy .
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