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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
P-gp/BCRP-IN-3
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "P-gp/BCRP-IN-3" in MCE Product Catalog:
Cat. No.: HY-189363
Target:
Research Areas:
P-gp/BCRP-IN-3 is a dual-target inhibitor that acts on P-gp (ABCB1) and BCRP (ABCG2) transporters. P-gp/BCRP-IN-3 directly binds to both transporters, blocks efflux function without affecting protein expression, and restores intracellular accumulation of chemotherapeutic substrates. P-gp/BCRP-IN-3 enhances tumor accumulation and antitumor activity of Mitoxantrone (HY-13502) in colorectal cancer xenograft models. P-gp/BCRP-IN-3 is applicable for cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
