1 Result for "

PARP1-IN-60

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PARP1-IN-60" in MCE Product Catalog:

Cat. No.: HY-189005
Target:  

PARP

Research Areas:  

Cancer

PARP1-IN-60 is an orally active PARP1 inhibitor with a human IC50 of 2.4 nM. PARP1-IN-60 selectively inhibits PARP1-mediated poly (ADP-ribosylation) (PARylation) compared with PARP2. PARP1-IN-60 induces DNA damage, G2/M phase arrest and antiproliferative activity in BRCA-deficient cells. PARP1-IN-60 can be used in the research of BRCA-mutant cancers and colorectal cancer .
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