1 Result for "

PBC 21

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PBC 21" in MCE Product Catalog:

製品番号: HY-184381
Target:  

Monoamine Oxidase

研究分野:  

Neurological Disease

PBC21 is an orally active, brain-penetrant, highly selective, mixed-type reversible MAO-B inhibitor (IC50 = 14 nM, SI for MAO-A > 2857). PBC21 exhibits no significant cytotoxicity across various human cell lines and demonstrates good metabolic stability in rat and human liver microsomes. In an MPTP (HY-W114750)-induced rat model of Parkinson's disease, PBC21 exhibits significantly improving motor function and positioning itself as a promising candidate for Parkinson's disease research .
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