2 Results for "

PC904

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "PC904" in MCE Product Catalog:

Cat. No.: HY-121195
CAS No.: 63469-19-2
Synonyms: PC-904
Target:  

Bacterial

Research Areas:  

Infection

Apalcillin (PC-904) in combination with Ro 48-1220, a penam sulfone β-lactamase inhibitor, demonstrated broad-spectrum activity against gram-negative aerobic and anaerobic bacteria, excluding Klebsiella oxytoca. It exhibited potent activity against β-lactamase-producing Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with effective MICs (11 μg/mL). The combination also inhibited Pseudomonas aeruginosa, Stenotrophomonas maltophilia, and Acinetobacter species at low MICs (0.25 to 4 μg/mL). However, its efficacy against oxacillin-resistant staphylococci and certain gram-positive organisms was limited. Apalcillin/Ro 48-1220 showed comparable efficacy to piperacillin/tazobactam against some extended-spectrum β-lactamase-producing Escherichia coli but was less effective against SHV-type β-lactamases .
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Cat. No.: HY-106705
CAS No.: 58795-03-2
Synonyms: PC-904 sodium
Target:  

Bacterial

Research Areas:  

Infection

Apalcillin (PC-904) (sodium) is an antibacterial agent. Apalcillin (sodium) is active against carbenicillin- and ampicillin-resistant strains of gram-negative bacilli .
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