1 Result for "

PD089828

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PD089828" in MCE Product Catalog:

Cat. No.: HY-112345
CAS No.: 179343-17-0
Purity:  98.07%
Target:  

FGFR PDGFR EGFR Src

Research Areas:  

Cancer

PD-089828 is an ATP competitive inhibitor of FGFR-1, PDGFR-β and EGFR (IC50s=0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of c-Src tyrosine kinase (IC50=0.18 µM). PD-089828 also inhibits MAPK with an IC50 of 7.1 µM. PD-089828 inhibits PDGF-, EGF- and bFGF-mediated tyrosine kinase receptor autophosphorylation in vitro. PD-089828 has a long-lasting cellular activity .
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