1 Result for "

PFK158

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "PFK158" in MCE Product Catalog:

11
11 Cited Publications
Cat. No.: HY-12203
CAS No.: 1462249-75-7
Purity:  98.88%
Target:  

Autophagy Apoptosis

Research Areas:  

Cancer

PFK-158 is a potent and selective PFKFB3 inhibitor with an IC50 value 137 nM. PFK-158 reduces glucose uptake, ATP production, lactate release, and induces apoptosis and autophagy in cancer cells. PFK-158 has broad anti-tumor activity. PFK-158 can also enhance Colistin's resistance to bacteria .
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